I am a breastfeeding mother and i want to know if it is safe to use Pentosan Polysulfate Sodium? Is Pentosan Polysulfate Sodium safe for nursing mother and child? Does Pentosan Polysulfate Sodium extracts into breast milk? Does Pentosan Polysulfate Sodium has any long term or short term side effects on infants? Can Pentosan Polysulfate Sodium influence milk supply or can Pentosan Polysulfate Sodium decrease milk supply in lactating mothers?

Pentosan Polysulfate Sodium lactation summary

Pentosan Polysulfate Sodium is safe in breastfeeding
  • DrLact safety Score for Pentosan Polysulfate Sodium is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Pentosan Polysulfate Sodium is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Pentosan Polysulfate Sodium does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Pentosan Polysulfate Sodium safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Pentosan Polysulfate Sodium usage in lactation

Sulfated polysaccharide of plant origin with anticoagulant and fibrinolytic properties similar to heparin. Topical, oral and parenteral administration (subcutaneous, intramuscular or intravenous).Orally used for pain relief of the urinary tract on interstitial cystitis.Topically used on superficial venous disorders, hemorrhoids and hematomas. At latest update relevant published data on its excretion into breast milk were not found. Because of a high molecular weight, excretion into breastmilk in significant amounts seems very unlikely.A low or not at all oral bioavailability (Faaij 1999, Simon 2005) makes it seems difficult the pass into the infant’s plasma through the breast milk ingested, except for premature infants and immediate neonatal period, in which there may be an increased intestinal permeability. Do not apply it on the chest to prevent the infant from ingesting it; if necessary, do it after a feeding and clean it up thoroughly with water before the next one.

Alternate Drugs for Vasoprotectives: Antihemorrhoidals, Antivaricose and Capillary stabilizing agents. ATC C05

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.