Is Pinaverium Bromide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pinaverium Bromide? Is Pinaverium Bromide safe for nursing mother and child? Does Pinaverium Bromide extracts into breast milk? Does Pinaverium Bromide has any long term or short term side effects on infants? Can Pinaverium Bromide influence milk supply or can Pinaverium Bromide decrease milk supply in lactating mothers?
Pinaverium Bromide lactation summary
- DrLact safety Score for Pinaverium Bromide is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Pinaverium Bromide may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Pinaverium Bromide may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Pinaverium Bromide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Pinaverium Bromide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Pinaverium Bromide usage in lactation
A Calcium channel blocker with spasmolytic activity on the intestine and antimuscarinic effects. At latest update no published data were found on excretion into breast milk.Pharmacokinetic data (moderately high molecular weight and high protein binding) make unlikely the passage into milk in significant amounts.Its low oral bioavailability hinders its passage into infant's plasma from ingested milk, except in preterm infants and immediate neonatal period, since they may exhibit an increased intestinal permeability. Anticholinergics may reduce milk production: take a minimum necessary dose and avoid prolonged treatment if decreased milk is observed.
Alternate Drugs for Drugs for functional bowel disorders (Anticholinergics, Antispasmodics). ATC A03A-B,
Dicyclomine(Unsafe)
Atropine(Safe)
Glycopyrrolate(Unsafe)
Belladona(Unsafe)
Dicycloverine(Unsafe)
Phloroglucinol(Low Risk)
Otilonium Bromide(Safe)
Glycopyrronium Bromide(Unsafe)
Hyoscyamine(Low Risk)
Mebeverine Hydrochloride(Low Risk)
Prifinium Bromide(Low Risk)
Propantheline-Bromide(Low Risk)
Trimebutine maleate(Low Risk)
Piperidolate Hydrochloride(Low Risk)
Phloroglucin(Low Risk)
Daturine(Low Risk)