Question

I am a breastfeeding mother and i want to know if it is safe to use Actimmune? Is Actimmune safe for nursing mother and child? Does Actimmune extracts into breast milk? Does Actimmune has any long term or short term side effects on infants? Can Actimmune influence milk supply or can Actimmune decrease milk supply in lactating mothers?

Answer by DrLact: About Actimmune usage in lactation

Interferon gamma is a normal component of human milk. No data are available on the use of exogenous interferon gamma 1b during breastfeeding. However, the amounts of the similar drugs, interferon alfa and interferon beta-1a, excreted into milk are very low. Any interferon in breastmilk is probably destroyed in the infant's gastrointestinal tract and not absorbed, except perhaps in neonates. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous interferon-gamma by an average about 10%.[1]

Alternate Drugs

Interferon Beta
Glatiramer(Low Risk)
Durvalumab
Avelumab
Dupilumab
Ocrelizumab
Atezolizumab
Peginterferon Beta
Pembrolizumab
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Interferon Alfacon-1
Interferon Gamma-1b

Synonyms of Actimmune

Interferon gamma-1b, recombinant
gamma Interferon 1B
IFN-gamma 1b
Interferon Gamma 1-b
UNII-21K6M2I7AG
HSDB 8137
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