Question

I am a breastfeeding mother and i want to know if it is safe to use gamma Interferon 1B? Is gamma Interferon 1B safe for nursing mother and child? Does gamma Interferon 1B extracts into breast milk? Does gamma Interferon 1B has any long term or short term side effects on infants? Can gamma Interferon 1B influence milk supply or can gamma Interferon 1B decrease milk supply in lactating mothers?

Answer by DrLact: About gamma Interferon 1B usage in lactation

Interferon gamma is a normal component of human milk. No data are available on the use of exogenous interferon gamma 1b during breastfeeding. However, the amounts of the similar drugs, interferon alfa and interferon beta-1a, excreted into milk are very low. Any interferon in breastmilk is probably destroyed in the infant's gastrointestinal tract and not absorbed, except perhaps in neonates. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous interferon-gamma by an average about 10%.[1]

Alternate Drugs

Interferon Gamma-1b
Interferon Beta
Glatiramer(Low Risk)
Durvalumab
Avelumab
Dupilumab
Ocrelizumab
Atezolizumab
Peginterferon Beta
Pembrolizumab
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Interferon Alfacon-1

Synonyms of gamma Interferon 1B

Actimmune
Interferon gamma-1b, recombinant
IFN-gamma 1b
Interferon Gamma 1-b
UNII-21K6M2I7AG
HSDB 8137
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