Is Nedocromil Sodium Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Nedocromil Sodium? Is Nedocromil Sodium safe for nursing mother and child? Does Nedocromil Sodium extracts into breast milk? Does Nedocromil Sodium has any long term or short term side effects on infants? Can Nedocromil Sodium influence milk supply or can Nedocromil Sodium decrease milk supply in lactating mothers?
Nedocromil Sodium lactation summary
- DrLact safety Score for Nedocromil Sodium is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Nedocromil Sodium is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Nedocromil Sodium does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Nedocromil Sodium safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Nedocromil Sodium usage in lactation
It is administered by inhalation for prevention of asthma and atopic rhinitis and as eye drops for allergic conjunctivitis. At latest update relevant published data on excretion into breast milk were not found. Pharmacokinetic data (very low bioavailability after inhalation, orally or ophthalmic application with very low plasma levels achieved, moderately elevated molecular weight and a high protein-binding capacity) would render it rather unlikely a significant passage into breastmilk, which would also cause a poor absorption through the infant’s gut . It is a well tolerated drug with indeed no side effects and none of them reportedly to be serious. The small dose used and low plasma absorption of most inhaled preparations (either buccal or nasal), topically apply as ophthalmologic or dermatologic preparations, make it unlikely any passage in a significant amount into breastmilk.
Answer by DrLact: About Nedocromil Sodium usage in lactation
Although no published data exist on the use of nedocromil during lactation, maternal milk levels are likely to be very low and it is expected to be poorly absorbed from the infant's gastrointestinal tract. If nedocromil is required by the mother, it is not a reason to discontinue breastfeeding.
Alternate Drugs for Decongestants & other nasal preparations for topical use. ATC R01A
Azelastine(Low Risk)
Oxymetazoline(Low Risk)
Ciclesonide(Safe)
Nedocromil(Safe)
Budesonide inhaled(Safe)
Naphazoline(Unsafe)
Xilometazoline(Unsafe)
Tramazoline(Unsafe)
Oxymetazoline Hydrochloride(Low Risk)
Naphazoline Hydrochloride(Unsafe)