Question

I am a breastfeeding mother and i want to know if it is safe to use AI3-15293? Is AI3-15293 safe for nursing mother and child? Does AI3-15293 extracts into breast milk? Does AI3-15293 has any long term or short term side effects on infants? Can AI3-15293 influence milk supply or can AI3-15293 decrease milk supply in lactating mothers?

AI3-15293 lactation summary

AI3-15293 is unsafe in breastfeeding
  • DrLact safety Score for AI3-15293 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of AI3-15293 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that AI3-15293 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using AI3-15293 .
  • It is recommended to evaluate the advantage of not breastfeeding while using AI3-15293 Vs not using AI3-15293 And continue breastfeeding.
  • While using AI3-15293 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About AI3-15293 usage in lactation

Pyrazolone derivative analgesic that inhibits Prostaglandin synthesis with an increased risk of medullar aplasia. Multiple compounds in association to caffeine, codeine, atropine and anti-inflammatory drugs are available. Overall, multi-drug associated compounds are not recommended especially while nursing. A single drug product should be .preferred. Ear drops containing this component are safe while nursing.

Answer by DrLact: About AI3-15293 usage in lactation

AI3-15293 is considered unlikely to harm the infant.[1] Because AI3-15293 is available only in ear drops, it is unlikely to be absorbed by the mother and reach the breastmilk. No special precautions are required during maternal use of AI3-15293-containing ear drops.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.