Is Josamycin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Josamycin? Is Josamycin safe for nursing mother and child? Does Josamycin extracts into breast milk? Does Josamycin has any long term or short term side effects on infants? Can Josamycin influence milk supply or can Josamycin decrease milk supply in lactating mothers?
Josamycin lactation summary
- DrLact safety Score for Josamycin is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Josamycin may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Josamycin may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Josamycin low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Josamycin We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Josamycin usage in lactation
A macrolide antibiotic that is approved for pediatric use. Frequently used in young infants At latest update no published data on excretion into breast milk were found. It has higher molecular weight and shorter half-life elimination span than other macrolide antibiotics like azithromycin and claritormycin that are excreted into breast milk in negligible amount.Until more published information about this drug regarding breastfeeding appears, it may be preferable a known and safer alternative, especially during the neonatal period and in cases of prematurity. Early exposure to macrolide antibiotics (especially erythromycin) has been linked to hypertrophic pyloric stenosis, even through breast milk, being it a reason to avoid them during the first month of breastfeeding. Take into account the possible negative results of bacterial cultures among febrile infants when their mothers are on antibiotics, as well as the possibility of gastroenteritis by altering the intestinal flora.
Alternate Drugs for Macrolide, Lincosamide and Streptogramin antibacterials. ATC J01F
Azithromycin(Safe)
Clarithromycin(Safe)
Clindamycin(Low Risk)
Telithromycin(Unsafe)
Roxithromycin(Safe)
Dalfopristin(Low Risk)
Dirithromycin(Low Risk)
Spiramycin(Safe)
Lincomycin(Safe)
Midecamycin(Low Risk)
Quinupristin(Low Risk)
Lincomycin Hydrochloride(Safe)