I am a breastfeeding mother and i want to know if it is safe to use Atovaquone mixture with proguanil? Is Atovaquone mixture with proguanil safe for nursing mother and child? Does Atovaquone mixture with proguanil extracts into breast milk? Does Atovaquone mixture with proguanil has any long term or short term side effects on infants? Can Atovaquone mixture with proguanil influence milk supply or can Atovaquone mixture with proguanil decrease milk supply in lactating mothers?
No information is available on the use of atovaquone and proguanil during breastfeeding. The Centers for Disease Control and Prevention does not currently recommend it for the prevention of malaria in women breastfeeding infants weighing less than 5 kg (11 pounds). However, it can be used for treatment of women who are breastfeeding infants of any weight when the potential benefit outweighs the potential risk to the infant (e.g., treating a breastfeeding woman who has acquired malaria in an area of multidrug-resistant strains and who cannot tolerate other treatment options).[1] In general, very small amounts of antimalarial drugs are excreted in the breast milk of lactating women. Because the quantity of antimalarial drugs transferred in breast milk is insufficient to provide adequate protection against malaria, infants who require chemoprophylaxis must also receive the recommended dosages of antimalarial drugs.[1]
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