Is dl-Hyoscyamine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use dl-Hyoscyamine? Is dl-Hyoscyamine safe for nursing mother and child? Does dl-Hyoscyamine extracts into breast milk? Does dl-Hyoscyamine has any long term or short term side effects on infants? Can dl-Hyoscyamine influence milk supply or can dl-Hyoscyamine decrease milk supply in lactating mothers?

Either isolated dose or topical medication are safe for breastfed babies. Anti-cholinergic drugs decrease Prolactin and Oxytocin hormone secretion. Long-standing dl-Hyoscyamine treatment could affects mother's milk production. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

No information is available on the use of dl-Hyoscyamine during breastfeeding. Long-term use of dl-Hyoscyamine might reduce milk production or milk letdown, but a single systemic or ophthalmic dose is not likely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.