Is Isopto-atropine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Isopto-atropine? Is Isopto-atropine safe for nursing mother and child? Does Isopto-atropine extracts into breast milk? Does Isopto-atropine has any long term or short term side effects on infants? Can Isopto-atropine influence milk supply or can Isopto-atropine decrease milk supply in lactating mothers?

Either isolated dose or topical medication are safe for breastfed babies. Anti-cholinergic drugs decrease Prolactin and Oxytocin hormone secretion. Long-standing Isopto-atropine treatment could affects mother's milk production. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

No information is available on the use of Isopto-atropine during breastfeeding. Long-term use of Isopto-atropine might reduce milk production or milk letdown, but a single systemic or ophthalmic dose is not likely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.