Question

I am a breastfeeding mother and i want to know if it is safe to use 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate? Is 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate safe for nursing mother and child? Does 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate extracts into breast milk? Does 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate has any long term or short term side effects on infants? Can 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate influence milk supply or can 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate decrease milk supply in lactating mothers?

1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate lactation summary

1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate is unsafe in breastfeeding
  • DrLact safety Score for 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate .
  • It is recommended to evaluate the advantage of not breastfeeding while using 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate Vs not using 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate And continue breastfeeding.
  • While using 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate usage in lactation

Use minimal dosage. Do not use on a long-term basis since anti-cholinergic drugs may decrease milk production. Not commercially available in Spain

Answer by DrLact: About 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate usage in lactation

No information is available on the use of 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate during breastfeeding. Because 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate is a quaternary ammonium compound, it is not likely to be absorbed and reach the bloodstream of the infant,[1][2][3] especially when given by inhalation or topically on the skin. Long-term oral use of 1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate might reduce milk production or milk letdown, but a single dose is unlikely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

1,1-Dimethyl-3-hydroxypyrrolidinium bromide alpha-cyclopentylmandelate Possible Effects in Breastfeeding

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[4][5][6][7][8] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[9] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.