Is N-Isopropylatropine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-Isopropylatropine? Is N-Isopropylatropine safe for nursing mother and child? Does N-Isopropylatropine extracts into breast milk? Does N-Isopropylatropine has any long term or short term side effects on infants? Can N-Isopropylatropine influence milk supply or can N-Isopropylatropine decrease milk supply in lactating mothers?
N-Isopropylatropine lactation summary
- DrLact safety Score for N-Isopropylatropine is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N-Isopropylatropine is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N-Isopropylatropine does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N-Isopropylatropine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-Isopropylatropine usage in lactation
At latest update no published data on excretion into breastmilk were found.
Because of a large volume of distribution along with a very low or undetectable plasma concentration reached after inhalation (Laurikainen 1988, Wood 1995), it must be very unlikely the passage of significant amounts into breastmilk.
Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested.
It has been used to treat newborns (Pediamecum 2015).
Experts and scientific societies consider the use of N-Isopropylatropine bromide during breastfeeding as devoid of risk to the infant (van Haren 1998, National Asthma Education 2004, Amir 2011).
Answer by DrLact: About N-Isopropylatropine usage in lactation
Although no published data exist on the use of N-Isopropylatropine, its use produces negligible maternal serum levels and any drug in breastmilk would not be absorbed by the infant. The risk to the breastfed infant of maternal N-Isopropylatropine inhalation is small.
Alternate Drugs
Salmeterol(Safe)
Ipratropium(Safe)
Arfomoterol(Low Risk)
Pirbuterol(Safe)
Aminophylline(Safe)
Zafirlukast(Low Risk)
Albuterol(Safe)
Dyphylline(Safe)
Levalbuterol(Safe)
Isoetharine(Safe)
Omalizumab(Low Risk)
Formoterol(Safe)
Cromolyn(Safe)
Nedocromil(Safe)
Fluticasone, Inhaled(Safe)
Montelukast(Safe)
Flunisolide(Safe)
Theophylline(Safe)
Terbutaline(Safe)
Salmeterol(Safe)
Ipratropium(Safe)
Arfomoterol(Low Risk)
Pirbuterol(Safe)
Aminophylline(Safe)
Glycopyrrolate(Unsafe)
Albuterol(Safe)
Dyphylline(Safe)
Levalbuterol(Safe)
Isoetharine(Safe)
Atropine(Safe)
Formoterol(Safe)
Epinephrine(Safe)
Theophylline(Safe)
Cyclopentolate(Low Risk)
Ipratropium(Safe)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Glycopyrrolate(Unsafe)
Oxybutinyn(Low Risk)
Atropine(Safe)
Flavoxate(Low Risk)
Dicyclomine(Unsafe)
Scopolamine(Low Risk)
Fesoterodine(Low Risk)
Tropicamide(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Glycopyrrolate(Unsafe)
Oxybutinyn(Low Risk)
Atropine(Safe)
Flavoxate(Low Risk)
Scopolamine(Low Risk)
Dicyclomine(Unsafe)
Fesoterodine(Low Risk)
Tropicamide(Low Risk)
Cyclopentolate(Low Risk)
Ipratropium(Safe)