Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-GR88G0I6UL? Is UNII-GR88G0I6UL safe for nursing mother and child? Does UNII-GR88G0I6UL extracts into breast milk? Does UNII-GR88G0I6UL has any long term or short term side effects on infants? Can UNII-GR88G0I6UL influence milk supply or can UNII-GR88G0I6UL decrease milk supply in lactating mothers?

UNII-GR88G0I6UL lactation summary

UNII-GR88G0I6UL is safe in breastfeeding
  • DrLact safety Score for UNII-GR88G0I6UL is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-GR88G0I6UL is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-GR88G0I6UL does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-GR88G0I6UL safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-GR88G0I6UL usage in lactation

At latest update no published data on excretion into breastmilk were found.

 Because of a large volume of distribution along with a very low or undetectable plasma concentration reached after inhalation (Laurikainen 1988, Wood 1995), it must be very unlikely the passage of significant amounts into breastmilk.
Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested.
It has been used to treat newborns (Pediamecum 2015). 

Experts and scientific societies consider the use of UNII-GR88G0I6UL bromide during breastfeeding as devoid of risk to the infant (van Haren 1998, National Asthma Education 2004, Amir 2011).

Answer by DrLact: About UNII-GR88G0I6UL usage in lactation

Although no published data exist on the use of UNII-GR88G0I6UL, its use produces negligible maternal serum levels and any drug in breastmilk would not be absorbed by the infant. The risk to the breastfed infant of maternal UNII-GR88G0I6UL inhalation is small.

Alternate Drugs

Omalizumab(Low Risk)
Cromolyn(Safe)
Arfomoterol(Low Risk)
Zafirlukast(Low Risk)
Albuterol(Safe)
Atropine(Safe)
Arfomoterol(Low Risk)
Albuterol(Safe)
Flavoxate(Low Risk)
Dicyclomine(Unsafe)
Scopolamine(Low Risk)
Fesoterodine(Low Risk)
Tropicamide(Low Risk)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Oxybutinyn(Low Risk)
Atropine(Safe)
Atropine(Safe)
Flavoxate(Low Risk)
Dicyclomine(Unsafe)
Scopolamine(Low Risk)
Fesoterodine(Low Risk)
Tropicamide(Low Risk)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Oxybutinyn(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.