Is Enoxolone Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Enoxolone? Is Enoxolone safe for nursing mother and child? Does Enoxolone extracts into breast milk? Does Enoxolone has any long term or short term side effects on infants? Can Enoxolone influence milk supply or can Enoxolone decrease milk supply in lactating mothers?
Enoxolone lactation summary
- DrLact safety Score for Enoxolone is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Enoxolone may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Enoxolone may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Enoxolone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Enoxolone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Enoxolone usage in lactation
Glycyrrhizinic acid derivative that is extracted from the root of licorice.Anti-inflammatory effect when topically applied (skin, mouth, throat and rectum). At latest update no published data on excretion into breast milk were found. It locally enhances the activity of hydrocortisone by inactivating a cortisol inhibiting enzyme, which can cause toxicity after systemic administration (see info on Licorice).It is unknown the level of absorption after dermal and oral rinses or application, with a reported case of systemic toxicity following topical use. Hence, it is not recommended a prolonged use of this product during lactation.It can cause contact dermatitis. Avoid applying it on the breast, otherwise, clean it thoroughly before breastfeeding.
Alternate Drugs for Treatment of wounds and ulcers: Cicatrizants & Enzymes. Act D03
Nitroglycerin(Safe)
Becaplermin(Low Risk)
Hydrocolloid Patch(Safe)
Isosorbide Dinitrate(Low Risk)
Glyceryl Trinitrate(Safe)
Pantothenic Acid(Safe)
Collagenase(Safe)
Panthenol(Safe)
Trinitrin(Safe)
Trinitroglycerin(Safe)
Glycyrrhetic Acid(Low Risk)
Glycyrrhetinic Acid(Low Risk)
Vitamin B3(Safe)
Vitamin B5(Safe)
Clostridiopeptidase A(Safe)
Rhpdgf-Bb(Low Risk)