Is Procaine Penicillin G Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Procaine Penicillin G? Is Procaine Penicillin G safe for nursing mother and child? Does Procaine Penicillin G extracts into breast milk? Does Procaine Penicillin G has any long term or short term side effects on infants? Can Procaine Penicillin G influence milk supply or can Procaine Penicillin G decrease milk supply in lactating mothers?

At latest update on excretion into breast milk of Penicillin procaine published information was not found. Mother plasma levels of Penicillin procaine have been shown to be lower than those of Penicillin G. Penicillin G is excreted into breast milk in non-significant amounts without side-effects observed among breastfed infants from treated mothers. Plasma levels in those infants were shown to be low or undetectable. Penicillin is a broad spectrum antibiotic that is commonly used in Pediatrics and Neonatology with very good tolerance even in premature newborns. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics. Eleventh WHO's Model List of Essential Drugs 2002: Compatible with breastfeeding.

Limited information indicates penicillin G produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Procaine penicillin G is acceptable in nursing mothers.

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of benzathine penicillin G intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[3]