Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7582? Is HSDB 7582 safe for nursing mother and child? Does HSDB 7582 extracts into breast milk? Does HSDB 7582 has any long term or short term side effects on infants? Can HSDB 7582 influence milk supply or can HSDB 7582 decrease milk supply in lactating mothers?

HSDB 7582 lactation summary

HSDB 7582 is safe in breastfeeding
  • DrLact safety Score for HSDB 7582 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 7582 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 7582 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 7582 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7582 usage in lactation

Pharmacokinetic data (moderately high molecular weight and high protein-binding capacity) explain an observed very low excretion into breastmilk (Datta 2016). A drug of the same group and similar effect, Zafirlukast, is also excreted into breastmilk in non-significant amounts. It is a licensed medication to be used in infants from 6 months of age on. Indeed, it has been used as early as 3 months of age with the same tolerance observed in older children.

Answer by DrLact: About HSDB 7582 usage in lactation

Very low levels of HSDB 7582 appear in breastmilk. HSDB 7582 is approved for use in children as young as 6 months of age and has been used in neonates in dosages far greater than the amounts in breastmilk. Amounts ingested by the infant would not be expected to cause any adverse effects in breastfed infants No special precautions are required.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.