Is UNII-MHM278SD3E Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-MHM278SD3E? Is UNII-MHM278SD3E safe for nursing mother and child? Does UNII-MHM278SD3E extracts into breast milk? Does UNII-MHM278SD3E has any long term or short term side effects on infants? Can UNII-MHM278SD3E influence milk supply or can UNII-MHM278SD3E decrease milk supply in lactating mothers?
UNII-MHM278SD3E lactation summary
- DrLact safety Score for UNII-MHM278SD3E is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-MHM278SD3E is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-MHM278SD3E does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-MHM278SD3E safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-MHM278SD3E usage in lactation
Pharmacokinetic data (moderately high molecular weight and high protein-binding capacity) explain an observed very low excretion into breastmilk (Datta 2016). A drug of the same group and similar effect, Zafirlukast, is also excreted into breastmilk in non-significant amounts. It is a licensed medication to be used in infants from 6 months of age on. Indeed, it has been used as early as 3 months of age with the same tolerance observed in older children.
Answer by DrLact: About UNII-MHM278SD3E usage in lactation
Very low levels of UNII-MHM278SD3E appear in breastmilk. UNII-MHM278SD3E is approved for use in children as young as 6 months of age and has been used in neonates in dosages far greater than the amounts in breastmilk. Amounts ingested by the infant would not be expected to cause any adverse effects in breastfed infants No special precautions are required.
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