Is 4-13-00-02742 (Beilstein Handbook Reference) Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use 4-13-00-02742 (Beilstein Handbook Reference)? Is 4-13-00-02742 (Beilstein Handbook Reference) safe for nursing mother and child? Does 4-13-00-02742 (Beilstein Handbook Reference) extracts into breast milk? Does 4-13-00-02742 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 4-13-00-02742 (Beilstein Handbook Reference) influence milk supply or can 4-13-00-02742 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

• DrLact safety Score for 4-13-00-02742 (Beilstein Handbook Reference) is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of 4-13-00-02742 (Beilstein Handbook Reference) may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that 4-13-00-02742 (Beilstein Handbook Reference) may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using 4-13-00-02742 (Beilstein Handbook Reference) .
• It is recommended to evaluate the advantage of not breastfeeding while using 4-13-00-02742 (Beilstein Handbook Reference) Vs not using 4-13-00-02742 (Beilstein Handbook Reference) And continue breastfeeding.
• While using 4-13-00-02742 (Beilstein Handbook Reference) Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Stupor, flatulence or vomiting have been described. Theoretical risk though never reported of bone marrow toxicity. Use only if necessary. Avoid any use during neonatal period. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics.

Adverse reactions such as vomiting, excessive intestinal gas and falling asleep at the breast have been reported in breastfed infants whose mothers were taking oral 4-13-00-02742 (Beilstein Handbook Reference). Milk concentrations are not sufficient to induce "gray baby" syndrome, but since 4-13-00-02742 (Beilstein Handbook Reference)-induced aplastic anemia is not dose-related, this might occur, but has not been reported. An alternate drug is preferred to 4-13-00-02742 (Beilstein Handbook Reference) during breastfeeding, especially while nursing a newborn or preterm infant. If the mother must receive 4-13-00-02742 (Beilstein Handbook Reference) during nursing, monitor the infant for gastrointestinal disturbances and adequacy of nursing. Monitoring of the infant's complete blood count and differential is advisable. In some cases, discontinuation of breastfeeding might be preferred.

One study reported 50 breastfed infants whose mothers were give oral 4-13-00-02742 (Beilstein Handbook Reference) beginning 2 to 12 days postpartum in dosages of 1 (n = 20), 2 (n = 20)or 3 grams (n = 10) daily. All of the infants refused to suck, and 50 to 60% fell asleep during nursing. Vomiting occurred after feeding in 10%, 25%, and 90% of infants with daily maternal dosages of 1, 2 and 3 grams, respectively. All infants had excessive intestinal gas and abdominal distention, with severe problems in 0.5%, 20% and 100% of infants with daily maternal dosages of 1, 2 and 3 grams, respectively.[4]