Is Difenidol Hydrochloride Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Difenidol Hydrochloride? Is Difenidol Hydrochloride safe for nursing mother and child? Does Difenidol Hydrochloride extracts into breast milk? Does Difenidol Hydrochloride has any long term or short term side effects on infants? Can Difenidol Hydrochloride influence milk supply or can Difenidol Hydrochloride decrease milk supply in lactating mothers?
Difenidol Hydrochloride lactation summary
- DrLact safety Score for Difenidol Hydrochloride is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Difenidol Hydrochloride may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Difenidol Hydrochloride may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Difenidol Hydrochloride low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Difenidol Hydrochloride We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Difenidol Hydrochloride usage in lactation
Used in the treatment of nausea and vomiting and vertigo in Ménière’s disease. Administered orally, intramuscularly or intravenously. Since the last update we have not found published data on its excretion in breast milk. It has a weak antimuscarinic action that could have negative effects on milk production in the first weeks postpartum. There is very little literature on this drug and it is sold in very few countries. It can cause severe symptoms at high doses (Yang 1998, JAMA 1968). Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity. If used during breastfeeding, a minimum effective dose is recommended for a limited time, monitoring for signs of irritability or drowsiness in the infant.
Alternate Drugs for Anti-vertigo Drug
Cinnarizine(Low Risk)
Betahistine(Low Risk)
Flunarizine Hydrochloride(Unsafe)
Diphenidol Hydrochloride(Low Risk)