Question

I am a breastfeeding mother and i want to know if it is safe to use Nifuroxazide? Is Nifuroxazide safe for nursing mother and child? Does Nifuroxazide extracts into breast milk? Does Nifuroxazide has any long term or short term side effects on infants? Can Nifuroxazide influence milk supply or can Nifuroxazide decrease milk supply in lactating mothers?

Nifuroxazide lactation summary

Nifuroxazide is safe in breastfeeding
  • DrLact safety Score for Nifuroxazide is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Nifuroxazide is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Nifuroxazide does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Nifuroxazide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Nifuroxazide usage in lactation

An antibacterial with very few bibliographical references which is used with little evidence of its efficacy (N.A.L. Prescrire 2004 and 1999) in the treatment of acute gastroenteritis of bacterial origin. Since the last update we have not found published data about its excretion in breast milk. It has a very low oral bioavailability, due to low or zero intestinal absorption (Armstrong 2015), making it unlikely its would pass into breast milk. Its low oral bioavailability would also further complicate its passing into the infant’s plasma via ingested breast milk, except in premature babies and in the immediate neonatal period during which there may be greater intestinal permeability.

Alternate Drugs for Antidiarrheals: Intestinal anti-infectives, adsorbents, electrolytes, anti-propulsive, anti-inflammatory and microorganisms agents. ATC A07

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.