Question

I am a breastfeeding mother and i want to know if it is safe to use Diphenoxilate-Hcl? Is Diphenoxilate-Hcl safe for nursing mother and child? Does Diphenoxilate-Hcl extracts into breast milk? Does Diphenoxilate-Hcl has any long term or short term side effects on infants? Can Diphenoxilate-Hcl influence milk supply or can Diphenoxilate-Hcl decrease milk supply in lactating mothers?

Diphenoxilate-Hcl lactation summary

Diphenoxilate-Hcl usage has low risk in breastfeeding
  • DrLact safety Score for Diphenoxilate-Hcl is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Diphenoxilate-Hcl may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Diphenoxilate-Hcl may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Diphenoxilate-Hcl low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Diphenoxilate-Hcl We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Diphenoxilate-Hcl usage in lactation

Opium derivated antidiarrheic drug. Check-up for sedation and constipation. It is not justified an indiscriminate use as a treatment of gastroenteritis. Most effective management of acute diarrheic disorders is aimed to keep hydration status by the use of WHO’s Oral Rehydration Solutions, and appropriate nutritional support. The use of drugs is not warranted since diarrheic disease is considered to be a self-limited condition. Not commercially available in Spain

Alternate Drugs for Antidiarrheals: Intestinal anti-infectives, adsorbents, electrolytes, anti-propulsive, anti-inflammatory and microorganisms agents. ATC A07

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