Is 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester? Is 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester safe for nursing mother and child? Does 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester extracts into breast milk? Does 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester has any long term or short term side effects on infants? Can 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester influence milk supply or can 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester decrease milk supply in lactating mothers?
3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester lactation summary
- DrLact safety Score for 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester usage in lactation
Dipeptide amino acid (Aspartic acid and Phenylalanine) which is used as a sweetener. Only after a high ingestion of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester phenylalanine would slightly increase in mother's milk with no harm effect on the normal child. It should not be cause of concern except in case of phenylketonuria.
Answer by DrLact: About 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester usage in lactation
3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester is not detectable in breastmilk after maternal ingestion because it is rapidly broken down in the mother's body. An extremely large intake of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester (equivalent to 17 cans of soda or 100 packets of Equal Sweetener) can slightly increase the amount of phenylalanine in breastmilk. Phenylalanine concentrations in milk return to baseline by 12 hours after a large single dose of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester. Although it is prudent to avoid the use of 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester in women who are nursing an infant with phenylketonuria, amounts that are typically ingested in 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester-sweetened foods and beverages do not result in any additional risk to breastfed infants with phenylketonuria.