Is Methyl N-L-alpha-aspartyl-L-phenylalaninate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Methyl N-L-alpha-aspartyl-L-phenylalaninate? Is Methyl N-L-alpha-aspartyl-L-phenylalaninate safe for nursing mother and child? Does Methyl N-L-alpha-aspartyl-L-phenylalaninate extracts into breast milk? Does Methyl N-L-alpha-aspartyl-L-phenylalaninate has any long term or short term side effects on infants? Can Methyl N-L-alpha-aspartyl-L-phenylalaninate influence milk supply or can Methyl N-L-alpha-aspartyl-L-phenylalaninate decrease milk supply in lactating mothers?
Methyl N-L-alpha-aspartyl-L-phenylalaninate lactation summary
- DrLact safety Score for Methyl N-L-alpha-aspartyl-L-phenylalaninate is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Methyl N-L-alpha-aspartyl-L-phenylalaninate is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Methyl N-L-alpha-aspartyl-L-phenylalaninate does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Methyl N-L-alpha-aspartyl-L-phenylalaninate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Methyl N-L-alpha-aspartyl-L-phenylalaninate usage in lactation
Dipeptide amino acid (Aspartic acid and Phenylalanine) which is used as a sweetener. Only after a high ingestion of Methyl N-L-alpha-aspartyl-L-phenylalaninate phenylalanine would slightly increase in mother's milk with no harm effect on the normal child. It should not be cause of concern except in case of phenylketonuria.
Answer by DrLact: About Methyl N-L-alpha-aspartyl-L-phenylalaninate usage in lactation
Methyl N-L-alpha-aspartyl-L-phenylalaninate is not detectable in breastmilk after maternal ingestion because it is rapidly broken down in the mother's body. An extremely large intake of Methyl N-L-alpha-aspartyl-L-phenylalaninate (equivalent to 17 cans of soda or 100 packets of Equal Sweetener) can slightly increase the amount of phenylalanine in breastmilk. Phenylalanine concentrations in milk return to baseline by 12 hours after a large single dose of Methyl N-L-alpha-aspartyl-L-phenylalaninate. Although it is prudent to avoid the use of Methyl N-L-alpha-aspartyl-L-phenylalaninate in women who are nursing an infant with phenylketonuria, amounts that are typically ingested in Methyl N-L-alpha-aspartyl-L-phenylalaninate-sweetened foods and beverages do not result in any additional risk to breastfed infants with phenylketonuria.