Is (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid? Is (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid safe for nursing mother and child? Does (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid extracts into breast milk? Does (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid has any long term or short term side effects on infants? Can (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid influence milk supply or can (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid decrease milk supply in lactating mothers?
(+-)-3-Benzoyl-alpha-methylbenzeneacetic acid lactation summary
- DrLact safety Score for (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid usage in lactation
(+-)-3-Benzoyl-alpha-methylbenzeneacetic acid is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.
Answer by DrLact: About (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid usage in lactation
Although (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid. Other agents are preferred, especially while nursing a newborn or preterm infant.
(+-)-3-Benzoyl-alpha-methylbenzeneacetic acid Side Effects in Breastfeeding
All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]
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