Question

I am a breastfeeding mother and i want to know if it is safe to use 2-(m-Benzoylphenyl)propionic acid? Is 2-(m-Benzoylphenyl)propionic acid safe for nursing mother and child? Does 2-(m-Benzoylphenyl)propionic acid extracts into breast milk? Does 2-(m-Benzoylphenyl)propionic acid has any long term or short term side effects on infants? Can 2-(m-Benzoylphenyl)propionic acid influence milk supply or can 2-(m-Benzoylphenyl)propionic acid decrease milk supply in lactating mothers?

2-(m-Benzoylphenyl)propionic acid lactation summary

2-(m-Benzoylphenyl)propionic acid is safe in breastfeeding
  • DrLact safety Score for 2-(m-Benzoylphenyl)propionic acid is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 2-(m-Benzoylphenyl)propionic acid is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 2-(m-Benzoylphenyl)propionic acid does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 2-(m-Benzoylphenyl)propionic acid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 2-(m-Benzoylphenyl)propionic acid usage in lactation

2-(m-Benzoylphenyl)propionic acid is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.

Answer by DrLact: About 2-(m-Benzoylphenyl)propionic acid usage in lactation

Although 2-(m-Benzoylphenyl)propionic acid has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking 2-(m-Benzoylphenyl)propionic acid. Other agents are preferred, especially while nursing a newborn or preterm infant.

2-(m-Benzoylphenyl)propionic acid Side Effects in Breastfeeding

All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, 2-(m-Benzoylphenyl)propionic acid was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]
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