Is CCRIS 4508 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 4508? Is CCRIS 4508 safe for nursing mother and child? Does CCRIS 4508 extracts into breast milk? Does CCRIS 4508 has any long term or short term side effects on infants? Can CCRIS 4508 influence milk supply or can CCRIS 4508 decrease milk supply in lactating mothers?

CCRIS 4508 is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.

Although CCRIS 4508 has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking CCRIS 4508. Other agents are preferred, especially while nursing a newborn or preterm infant.

All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, CCRIS 4508 was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]