Question

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 4508? Is CCRIS 4508 safe for nursing mother and child? Does CCRIS 4508 extracts into breast milk? Does CCRIS 4508 has any long term or short term side effects on infants? Can CCRIS 4508 influence milk supply or can CCRIS 4508 decrease milk supply in lactating mothers?

CCRIS 4508 lactation summary

CCRIS 4508 is safe in breastfeeding
  • DrLact safety Score for CCRIS 4508 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of CCRIS 4508 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that CCRIS 4508 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of CCRIS 4508 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About CCRIS 4508 usage in lactation

CCRIS 4508 is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.

Answer by DrLact: About CCRIS 4508 usage in lactation

Although CCRIS 4508 has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking CCRIS 4508. Other agents are preferred, especially while nursing a newborn or preterm infant.

CCRIS 4508 Side Effects in Breastfeeding

All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, CCRIS 4508 was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.