Is Ketoprofeno Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Ketoprofeno? Is Ketoprofeno safe for nursing mother and child? Does Ketoprofeno extracts into breast milk? Does Ketoprofeno has any long term or short term side effects on infants? Can Ketoprofeno influence milk supply or can Ketoprofeno decrease milk supply in lactating mothers?

Ketoprofeno is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.

Although Ketoprofeno has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking Ketoprofeno. Other agents are preferred, especially while nursing a newborn or preterm infant.

All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, Ketoprofeno was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]