Is Cartrol Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Cartrol? Is Cartrol safe for nursing mother and child? Does Cartrol extracts into breast milk? Does Cartrol has any long term or short term side effects on infants? Can Cartrol influence milk supply or can Cartrol decrease milk supply in lactating mothers?

• DrLact safety Score for Cartrol is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Cartrol may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Cartrol may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Cartrol .
• It is recommended to evaluate the advantage of not breastfeeding while using Cartrol Vs not using Cartrol And continue breastfeeding.
• While using Cartrol Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

At date of last update were not found published data on its excretion into breast milk, Pharmacokinetic data (low protein-binding capacity) make likely excretion into breast milk in amounts that could be significant. Until more information on this drug is available, it is preferred other options that are known to be safer, especially during the neonatal period or in cases of prematurity. Because of a small dose and low absorption to the plasma in a majority of ophthalmic preparations that are topically used, a significant excretion into the milk is unlikely, thus it is considered of very low risk while breastfeeding in this cases. It would be advisable to press on the lacrimal area or tightly close the eyes for a couple of minutes (nasolacrimal occlusion) to minimize the systemic absorption.

No data are available for the use of Cartrol during breastfeeding. Because its excretion into breastmilk is probably extensive, other beta-adrenergic blocking drugs are preferred to oral Cartrol while breastfeeding a neonate. Infants over 2 months of age have more mature kidney function and are less likely to be affected. Ophthalmic use of Cartrol by the mother should pose little risk to the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated.. None of the mothers were taking Cartrol.[2] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[3][4]

A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[5] There are no reports on the effects of beta-blockade or Cartrol use during normal lactation.