Question

I am a breastfeeding mother and i want to know if it is safe to use Dimetindene Maleate (Topical use)? Is Dimetindene Maleate (Topical use) safe for nursing mother and child? Does Dimetindene Maleate (Topical use) extracts into breast milk? Does Dimetindene Maleate (Topical use) has any long term or short term side effects on infants? Can Dimetindene Maleate (Topical use) influence milk supply or can Dimetindene Maleate (Topical use) decrease milk supply in lactating mothers?

Dimetindene Maleate (Topical use) lactation summary

Dimetindene Maleate (Topical use) is safe in breastfeeding
  • DrLact safety Score for Dimetindene Maleate (Topical use) is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Dimetindene Maleate (Topical use) is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Dimetindene Maleate (Topical use) does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Dimetindene Maleate (Topical use) safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dimetindene Maleate (Topical use) usage in lactation

First generation antihistamine, alkylamine, with sedative and antimuscarinic effect.It is used in the form of gel or cream for itchy skin relief. At latest update no published data on excretion into breast milk was found. Because a low dermal absorption and high plasma protein binding capacity, the passage of a significant amount into breast milk is unlikely. Do not apply on the chest to prevent ingestion by the infant; otherwise, apply it after having nursed the infant and rinse it thoroughly with water before the next feeding.Avoid applying creams, gels and other local application product containing paraffin to the nipple (mineral oil) for the infant not absorbed. The systemic use (oral, nasal or intravenous inhalation) during breastfeedingis considered to risky. See Dimethindene maleate (systemic use)

Alternate Drugs for Antipruritics, Topical Use (Antihistamines, Anesthetics). ATC D04A.

Calamine(Safe)
Doxepin Cream(Unsafe)
Tripelennamine Topical Use(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.