Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-G32F6EID2H? Is UNII-G32F6EID2H safe for nursing mother and child? Does UNII-G32F6EID2H extracts into breast milk? Does UNII-G32F6EID2H has any long term or short term side effects on infants? Can UNII-G32F6EID2H influence milk supply or can UNII-G32F6EID2H decrease milk supply in lactating mothers?

UNII-G32F6EID2H lactation summary

UNII-G32F6EID2H is safe in breastfeeding
  • DrLact safety Score for UNII-G32F6EID2H is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-G32F6EID2H is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-G32F6EID2H does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-G32F6EID2H safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-G32F6EID2H usage in lactation

Antibacterial carbapenem beta-lactam with indications similar to imipenem.Intravenous administration a daily dose. It is excreted in breast milk in a clinically insignificant amount (Merck 2012). Authorized pediatric use in infants from 3 months of age. Its low oral bioavailability would make it difficult for it to pass to the infant’s plasma ingesting breast milk, except in preterm infants and in the immediate neonatal period when there may be increased intestinal permeability. The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).

Answer by DrLact: About UNII-G32F6EID2H usage in lactation

Limited information indicates that UNII-G32F6EID2H produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush has been reported with beta-lactams, but these effects have not been adequately evaluated. UNII-G32F6EID2H is acceptable in nursing mothers.

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