Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 8020? Is HSDB 8020 safe for nursing mother and child? Does HSDB 8020 extracts into breast milk? Does HSDB 8020 has any long term or short term side effects on infants? Can HSDB 8020 influence milk supply or can HSDB 8020 decrease milk supply in lactating mothers?

HSDB 8020 lactation summary

HSDB 8020 is safe in breastfeeding
  • DrLact safety Score for HSDB 8020 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 8020 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 8020 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 8020 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 8020 usage in lactation

Antibacterial carbapenem beta-lactam with indications similar to imipenem.Intravenous administration a daily dose. It is excreted in breast milk in a clinically insignificant amount (Merck 2012). Authorized pediatric use in infants from 3 months of age. Its low oral bioavailability would make it difficult for it to pass to the infant’s plasma ingesting breast milk, except in preterm infants and in the immediate neonatal period when there may be increased intestinal permeability. The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).

Answer by DrLact: About HSDB 8020 usage in lactation

Limited information indicates that HSDB 8020 produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush has been reported with beta-lactams, but these effects have not been adequately evaluated. HSDB 8020 is acceptable in nursing mothers.

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Nafcillin(Safe)
Erythromycin(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Indinavir(Unsafe)
Ertapenem(Safe)
Demeclocycline(Low Risk)
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Econazole(Safe)
Tenofovir(Safe)
Ganciclovir(Low Risk)
Cefprozil(Safe)
Lindane(Unsafe)
Aztreonam(Safe)
Acyclovir(Safe)
Primaquine(Low Risk)
Methicillin(Low Risk)
Quinine(Safe)
Cefdinir(Safe)
Efavirenz(Unsafe)
Saquinavir(Unsafe)
Atovaquone(Low Risk)
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Abacavir(Safe)
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Naftifine(Safe)
Dapsone(Low Risk)
Doxycycline(Low Risk)
Nelfinavir(Unsafe)
Neomycin(Safe)
Cefaclor(Safe)
Nalidixic Acid(Low Risk)
Levofloxacin(Low Risk)
Amikacin(Safe)
Nafcillin(Safe)
Erythromycin(Low Risk)
Demeclocycline(Low Risk)
Iodine(Unsafe)
Cefixime(Safe)
Kanamycin(Safe)
Ertapenem(Safe)
Moxifloxacin(Low Risk)
Clindamycin(Low Risk)
Cefepime(Safe)
Cefprozil(Safe)
Aztreonam(Safe)
Methicillin(Low Risk)
Cefdinir(Safe)
Ofloxacin(Safe)
Methenamine(Unsafe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Doxycycline(Low Risk)
Neomycin(Safe)
Cefaclor(Safe)
Lomefloxacin(Low Risk)
Mupirocin(Safe)
Capreomycin(Low Risk)
Ertapenem(Safe)
Meropenem(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.