Question

I am a breastfeeding mother and i want to know if it is safe to use 123I-Iodohippuran? Is 123I-Iodohippuran safe for nursing mother and child? Does 123I-Iodohippuran extracts into breast milk? Does 123I-Iodohippuran has any long term or short term side effects on infants? Can 123I-Iodohippuran influence milk supply or can 123I-Iodohippuran decrease milk supply in lactating mothers?

Answer by DrLact: About 123I-Iodohippuran usage in lactation

Information in this record refers to the use of 123I-Iodohippuran (I 123 ortho-iodohippurate; I 123 OIH) as a kidney function diagnostic agent. The United States Nuclear Regulatory Commission states that breastfeeding need not be interrupted after administration of I 123 OIH in doses up to 100 MBq (4 mCi) to a nursing mother.[1] However, some experts recommend nursing the infant just before administration of the radiopharmaceutical and interrupting breastfeeding for 8 to 12 hours after the dose.[2][3] If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption.[2][4][5] Mothers need not refrain from close contact with their infants after usual clinical doses.[6] Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[7]

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