Question

I am a breastfeeding mother and i want to know if it is safe to use Cyproterone Acetate? Is Cyproterone Acetate safe for nursing mother and child? Does Cyproterone Acetate extracts into breast milk? Does Cyproterone Acetate has any long term or short term side effects on infants? Can Cyproterone Acetate influence milk supply or can Cyproterone Acetate decrease milk supply in lactating mothers?

Cyproterone Acetate lactation summary

Cyproterone Acetate is unsafe in breastfeeding
  • DrLact safety Score for Cyproterone Acetate is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Cyproterone Acetate may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Cyproterone Acetate may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Cyproterone Acetate .
  • It is recommended to evaluate the advantage of not breastfeeding while using Cyproterone Acetate Vs not using Cyproterone Acetate And continue breastfeeding.
  • While using Cyproterone Acetate Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Cyproterone Acetate usage in lactation

Progestogen with antiandrogenic properties that is used for the treatment of conditions with hypersexuality, prostate carcinoma, transsexualism and, together with ethinyl estradiol, for hirsutism, acne and alopecia and hyperandrogenism in women. It is excreted into breast milk in small quantities (Stoppelli 1980), but their anti-androgenic effects could be clinically significant for the infant when doses of 50 milligrams per day or higher are used. The small amount (2 mg) contained in contraceptive tablets in which it is combined with ethinyl estradiol would represent a very low risk and would be compatible with breastfeeding.

Alternate Drugs for Sex hormone antagonists and modulators of the genital system. ATC G03H & G03X

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