Is Capreomycine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Capreomycine? Is Capreomycine safe for nursing mother and child? Does Capreomycine extracts into breast milk? Does Capreomycine has any long term or short term side effects on infants? Can Capreomycine influence milk supply or can Capreomycine decrease milk supply in lactating mothers?

Systemic absorption is minimal.

Developmental problems have been reported in two infants exposed to Capreomycine in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to Capreomycine. Because Capreomycine is not orally absorbed it is unlikely to adversely affect the breastfed infant. If Capreomycine is required by the mother, it is not a reason to discontinue breastfeeding.

Capreomycine was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]