Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-232HYX66HC? Is UNII-232HYX66HC safe for nursing mother and child? Does UNII-232HYX66HC extracts into breast milk? Does UNII-232HYX66HC has any long term or short term side effects on infants? Can UNII-232HYX66HC influence milk supply or can UNII-232HYX66HC decrease milk supply in lactating mothers?

UNII-232HYX66HC lactation summary

UNII-232HYX66HC usage has low risk in breastfeeding
  • DrLact safety Score for UNII-232HYX66HC is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-232HYX66HC may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-232HYX66HC may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-232HYX66HC low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-232HYX66HC We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-232HYX66HC usage in lactation

Systemic absorption is minimal.

Answer by DrLact: About UNII-232HYX66HC usage in lactation

Developmental problems have been reported in two infants exposed to UNII-232HYX66HC in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to UNII-232HYX66HC. Because UNII-232HYX66HC is not orally absorbed it is unlikely to adversely affect the breastfed infant. If UNII-232HYX66HC is required by the mother, it is not a reason to discontinue breastfeeding.

UNII-232HYX66HC Side Effects in Breastfeeding

UNII-232HYX66HC was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]

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Amikacin(Safe)
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Primaquine(Low Risk)
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Atovaquone(Low Risk)
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Demeclocycline(Low Risk)
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Cefixime(Safe)
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Kanamycin(Safe)
Malathion(Low Risk)
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Methicillin(Low Risk)
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Rifaximin(Safe)
Nelfinavir(Unsafe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Capreomycin(Low Risk)
Enoxacin(Low Risk)
Cefotetan(Safe)
Ertapenem(Safe)
Cefaclor(Safe)
Doxycycline(Low Risk)
Iodine(Unsafe)
Neomycin(Safe)
Lomefloxacin(Low Risk)
Amikacin(Safe)
Nalidixic Acid(Low Risk)
Erythromycin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Kanamycin(Safe)
Clindamycin(Low Risk)
Cefepime(Safe)
Moxifloxacin(Low Risk)
Cefprozil(Safe)
Aztreonam(Safe)
Cefdinir(Safe)
Methicillin(Low Risk)
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Gatifloxacin(Low Risk)
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.