Is UNII-8W5C518302 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-8W5C518302? Is UNII-8W5C518302 safe for nursing mother and child? Does UNII-8W5C518302 extracts into breast milk? Does UNII-8W5C518302 has any long term or short term side effects on infants? Can UNII-8W5C518302 influence milk supply or can UNII-8W5C518302 decrease milk supply in lactating mothers?
UNII-8W5C518302 lactation summary
- DrLact safety Score for UNII-8W5C518302 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-8W5C518302 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-8W5C518302 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-8W5C518302 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-8W5C518302 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-8W5C518302 usage in lactation
One case of hemolytic anemia has been described. Check-up for development of jaundice in the infant. Avoid its use in patients affected of G-6-PD deficiency. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About UNII-8W5C518302 usage in lactation
UNII-8W5C518302 can be used during breastfeeding; however, hemolytic anemia might occur, especially in newborn infants and in those with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The time of greatest risk for hemolysis in fullterm newborns without G6PD deficiency might be as short as 8 days after birth.[1] One source states that use of UNII-8W5C518302 in the treatment of leprosy is advantageous because it kills the organisms in breastmilk.[2] Monitor the infant for signs of hemolysis, especially in newborn or premature breastfed infants. Topical UNII-8W5C518302 gel used to treat acne has not been studied during breastfeeding. According to the manufacturer, topical UNII-8W5C518302 gel results in a blood level of 1% that of a 100 mg oral dose. It is unlikely that the topical gel would affect the breastfed infant, but the manufacturer states that it should not be used during nursing. Until more data are available, an alternative topical agent might be preferred.
UNII-8W5C518302 Side Effects in Breastfeeding
A case of mild hemolytic anemia occurred in a 41-day-old breastfed infant whose mother was taking UNII-8W5C518302 50 mg daily. The hemolysis was probably caused by UNII-8W5C518302 in milk.[3] A woman with leprosy took UNII-8W5C518302, clofazimine and rifampin during pregnancy and breastfeeding. Her infant developed skin discoloration attributed to clofazimine which reversed 3 months after cessation of breastfeeding.[5]
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