Question

I am a breastfeeding mother and i want to know if it is safe to use Estriol (Topical Use)? Is Estriol (Topical Use) safe for nursing mother and child? Does Estriol (Topical Use) extracts into breast milk? Does Estriol (Topical Use) has any long term or short term side effects on infants? Can Estriol (Topical Use) influence milk supply or can Estriol (Topical Use) decrease milk supply in lactating mothers?

Estriol (Topical Use) lactation summary

Estriol (Topical Use) usage has low risk in breastfeeding
  • DrLact safety Score for Estriol (Topical Use) is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Estriol (Topical Use) may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Estriol (Topical Use) may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Estriol (Topical Use) low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Estriol (Topical Use) We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Estriol (Topical Use) usage in lactation

Estrogenic drug for topical use with trophic effect on vaginal mucosa. While breastfeeding, non-hormonal lubricants (cream, jelly or ovules) are preferred agents for treatment of vaginal dryness due to hypo-estrogenic stimulation than those estrogenic-containing topical agents since their long lasting use may lowers breast-milk production.

Alternate Drugs for Estrogens. ATC G03C

Estradiol(Low Risk)
Ethinyl Estradiol(Low Risk)
Estradiol Valerate(Low Risk)
Ethinylestradiol(Low Risk)
Promestriene(Low Risk)
Chlorotrianisene(Unsafe)
Diethylstilbestrol(Dangerous)
Dihydrofolliculin(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.