I am a breastfeeding mother and i want to know if it is safe to use Bayer 5312? Is Bayer 5312 safe for nursing mother and child? Does Bayer 5312 extracts into breast milk? Does Bayer 5312 has any long term or short term side effects on infants? Can Bayer 5312 influence milk supply or can Bayer 5312 decrease milk supply in lactating mothers?
Minimal information exists on the use of Bayer 5312 during breastfeeding. Although some developmental problems have been reported in two infants exposed to Bayer 5312 in breastmilk, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to Bayer 5312. If Bayer 5312 is required by the mother of an older infant, it is not a reason to discontinue breastfeeding, but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Bayer 5312 was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]
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