Question

I am a breastfeeding mother and i want to know if it is safe to use BRN 0116474? Is BRN 0116474 safe for nursing mother and child? Does BRN 0116474 extracts into breast milk? Does BRN 0116474 has any long term or short term side effects on infants? Can BRN 0116474 influence milk supply or can BRN 0116474 decrease milk supply in lactating mothers?

Answer by DrLact: About BRN 0116474 usage in lactation

Minimal information exists on the use of BRN 0116474 during breastfeeding. Although some developmental problems have been reported in two infants exposed to BRN 0116474 in breastmilk, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to BRN 0116474. If BRN 0116474 is required by the mother of an older infant, it is not a reason to discontinue breastfeeding, but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

BRN 0116474 Side Effects in Breastfeeding

BRN 0116474 was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]
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