Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7473? Is HSDB 7473 safe for nursing mother and child? Does HSDB 7473 extracts into breast milk? Does HSDB 7473 has any long term or short term side effects on infants? Can HSDB 7473 influence milk supply or can HSDB 7473 decrease milk supply in lactating mothers?

Answer by DrLact: About HSDB 7473 usage in lactation

Minimal information exists on the use of HSDB 7473 during breastfeeding. Although some developmental problems have been reported in two infants exposed to HSDB 7473 in breastmilk, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to HSDB 7473. If HSDB 7473 is required by the mother of an older infant, it is not a reason to discontinue breastfeeding, but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

HSDB 7473 Side Effects in Breastfeeding

HSDB 7473 was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]
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