Is (2-Hydroxypropyl)trimethylammonium carbamate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use (2-Hydroxypropyl)trimethylammonium carbamate? Is (2-Hydroxypropyl)trimethylammonium carbamate safe for nursing mother and child? Does (2-Hydroxypropyl)trimethylammonium carbamate extracts into breast milk? Does (2-Hydroxypropyl)trimethylammonium carbamate has any long term or short term side effects on infants? Can (2-Hydroxypropyl)trimethylammonium carbamate influence milk supply or can (2-Hydroxypropyl)trimethylammonium carbamate decrease milk supply in lactating mothers?

• DrLact safety Score for (2-Hydroxypropyl)trimethylammonium carbamate is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of (2-Hydroxypropyl)trimethylammonium carbamate may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that (2-Hydroxypropyl)trimethylammonium carbamate may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using (2-Hydroxypropyl)trimethylammonium carbamate .
• It is recommended to evaluate the advantage of not breastfeeding while using (2-Hydroxypropyl)trimethylammonium carbamate Vs not using (2-Hydroxypropyl)trimethylammonium carbamate And continue breastfeeding.
• While using (2-Hydroxypropyl)trimethylammonium carbamate Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

It has been described one case of diarrhea and abdominal pain in the infant. Withdrawn from market in Spain.

No information is available on the use of (2-Hydroxypropyl)trimethylammonium carbamate during breastfeeding. If it is used during breastfeeding, monitor the infant for signs of cholinergic excess (diarrhea, lacrimation, and excessive salivation or urination), especially in younger, exclusively breastfed infants.

Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release,[1] and have variable effects on serum prolactin.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.