Question

I am a breastfeeding mother and i want to know if it is safe to use LK 14304-18? Is LK 14304-18 safe for nursing mother and child? Does LK 14304-18 extracts into breast milk? Does LK 14304-18 has any long term or short term side effects on infants? Can LK 14304-18 influence milk supply or can LK 14304-18 decrease milk supply in lactating mothers?

LK 14304-18 lactation summary

LK 14304-18 is safe in breastfeeding
  • DrLact safety Score for LK 14304-18 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of LK 14304-18 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that LK 14304-18 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of LK 14304-18 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About LK 14304-18 usage in lactation

Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding. Systemic absorption is minimal. There have not been problems except when a maternal overdose was absorbed.

Answer by DrLact: About LK 14304-18 usage in lactation

Limited information indicates that maternal use of LK 14304-18 0.2% ophthalmic drops do not adversely affect their nursing infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue. Topical LK 14304-18 gel used to treat rosacea has not been studied during breastfeeding. It is unlikely that the topical gel would affect the breastfed infant, but the manufacturer states that it should not be used during nursing. Until more data are available, an alternative topical agent might be preferred

LK 14304-18 Side Effects in Breastfeeding

A woman used LK 14304-18 0.2%, timolol gel-forming solution 0.5%, dipiverin 0.2%, and dorzolamide 0.5% drops for glaucoma while nursing a newborn. The frequency of medication use and extent of nursing were not stated. All medications were given immediately after nursing with punctal occlusion of the tear duct. The infant's vital signs were closely monitored with no signs of bradycardia or apnea.[1] A woman was using ophthalmic drops containing 0.5% timolol and 0.2% LK 14304-18 twice daily in the right eye for 6 months. During this time, she breastfed her infant (extent not stated) apparently without harm to her infant.[2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.