Question

I am a breastfeeding mother and i want to know if it is safe to use Sulfamethoxazole & Trimethoprim? Is Sulfamethoxazole & Trimethoprim safe for nursing mother and child? Does Sulfamethoxazole & Trimethoprim extracts into breast milk? Does Sulfamethoxazole & Trimethoprim has any long term or short term side effects on infants? Can Sulfamethoxazole & Trimethoprim influence milk supply or can Sulfamethoxazole & Trimethoprim decrease milk supply in lactating mothers?

Sulfamethoxazole & Trimethoprim lactation summary

Sulfamethoxazole & Trimethoprim is safe in breastfeeding
  • DrLact safety Score for Sulfamethoxazole & Trimethoprim is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Sulfamethoxazole & Trimethoprim is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Sulfamethoxazole & Trimethoprim does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Sulfamethoxazole & Trimethoprim safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Sulfamethoxazole & Trimethoprim usage in lactation

Mixture of 5 parts of Sulfamethoxazole and 1 part of Trimethoprim. See info on items separately. Trimethoprim is excreted into breast milk at 4 to 10% of corrected pediatric dose. No adverse effects have been shown in breastfed infants. Used for treatment of infants older than one month. Sulfamethoxazole is excreted in low levels into breast milk.No adverse effects have been shown in breastfed infants. Cautious use for treatment of premature infants with hyperbilirubinemia or G-6-P-D deficiency is required. Avoid use in affected patients . Check-up for infant jaundice. Be aware of false negative results of bacterial cultures when the mother is on antibiotics and diarrheal disease due to intestinal flora imbalance. The American Academy of Pediatrics rates it compatible with breastfeeding. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding for older, healthy full- term infants. See below the information of these related products:

Alternate Drugs for Antibacterials Sulfonamides and Trimethoprim. ATC J01E

Trimethoprim(Safe)
Sulfisoxazole(Safe)
Sulfamethoxazole(Safe)
Phthalylsulfathiazole(Safe)
Sulfadiazine(Low Risk)
Sulfafurazole(Safe)
TMP(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.