Is TL 457 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use TL 457? Is TL 457 safe for nursing mother and child? Does TL 457 extracts into breast milk? Does TL 457 has any long term or short term side effects on infants? Can TL 457 influence milk supply or can TL 457 decrease milk supply in lactating mothers?
TL 457 lactation summary
- DrLact safety Score for TL 457 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of TL 457 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that TL 457 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of TL 457 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using TL 457 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About TL 457 usage in lactation
Systemic absorption is minimal. There have not been associated problems except when a maternal overdose was absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding.
Answer by DrLact: About TL 457 usage in lactation
No information is available on the use of TL 457 ophthalmic drops during breastfeeding. Because of its short half-life, it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.
TL 457 Possible Effects in Breastfeeding
Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release,[1] and have variable effects on serum prolactin.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs
Carbachol(Low Risk)
Pilocarpine(Unsafe)
Carbachol(Low Risk)
Bethanechol(Unsafe)
Pilocarpine(Unsafe)
Carbachol(Low Risk)
Bethanechol(Unsafe)
Pyridostigmine(Safe)
Pilocarpine(Unsafe)