I am a breastfeeding mother and i want to know if it is safe to use Isosorbide Mononitrate? Is Isosorbide Mononitrate safe for nursing mother and child? Does Isosorbide Mononitrate extracts into breast milk? Does Isosorbide Mononitrate has any long term or short term side effects on infants? Can Isosorbide Mononitrate influence milk supply or can Isosorbide Mononitrate decrease milk supply in lactating mothers?

Isosorbide Mononitrate lactation summary

Isosorbide Mononitrate usage has low risk in breastfeeding
  • DrLact safety Score for Isosorbide Mononitrate is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Isosorbide Mononitrate may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Isosorbide Mononitrate may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Isosorbide Mononitrate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Isosorbide Mononitrate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Isosorbide Mononitrate usage in lactation

The amount of nitrates in breast milk is not related to level of contamination in drinking water (ingest <100 mg/day of nitrate do not produce milk with elevated nitrate levels). By this reason, breastfed babies from regions with nitrate contaminated water do not have increased risk of Metahemoglobinemia like bottle-fed babies do. The amount of nitrate compounds contained in vasodilator medication is so small that no problems have been reported while breastfeeding.

Alternate Drugs for Vasodilators and other cardiac preparations. ATC C01D-E

Coenzyme Q10(Low Risk)
Ubidecarenone(Low Risk)
Ubiquinone 10(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.