Is UNII-M2F465ROXU Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-M2F465ROXU? Is UNII-M2F465ROXU safe for nursing mother and child? Does UNII-M2F465ROXU extracts into breast milk? Does UNII-M2F465ROXU has any long term or short term side effects on infants? Can UNII-M2F465ROXU influence milk supply or can UNII-M2F465ROXU decrease milk supply in lactating mothers?
UNII-M2F465ROXU lactation summary
- DrLact safety Score for UNII-M2F465ROXU is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-M2F465ROXU may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-M2F465ROXU may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-M2F465ROXU low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-M2F465ROXU We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-M2F465ROXU usage in lactation
It is composed by bisphosphonates. Most bisphosphonates are acidic compounds that achieve low plasma concentration. Both features make it unlikely excretion into the milk in clinically significant amount. Intestinal absorption of bisphosphonates is very low even during fasting and is considered negligible in the presence of milk due to formation with the calcium of non absorbable compounds. A latest update no published data were found on excretion in the breast milk. Until more data about this drug regarding breastfeeding is available, safer known alternatives (pamidronate) should be of choice, especially in the neonatal period and in case of prematurity.
Answer by DrLact: About UNII-M2F465ROXU usage in lactation
Because no information is available on the use of UNII-M2F465ROXU during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. However, absorption of UNII-M2F465ROXU by a breastfed infant is unlikely.
Alternate Drugs
Alendronate(Low Risk)
Risedronate(Low Risk)
Ibandronate(Low Risk)
Alendronate(Low Risk)
Risedronate(Low Risk)
Ibandronate(Low Risk)
Calcitriol(Safe)
Risedronate(Low Risk)
Ibandronate(Low Risk)
Alendronate(Low Risk)