Is Sch 58235 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Sch 58235? Is Sch 58235 safe for nursing mother and child? Does Sch 58235 extracts into breast milk? Does Sch 58235 has any long term or short term side effects on infants? Can Sch 58235 influence milk supply or can Sch 58235 decrease milk supply in lactating mothers?

Reduces intestinal absorption of cholesterol and phytosterols (AEMPS 2016, Merck 2007). Since the last update we have not found published data in relation to breastfeeding. Its high binding to plasma proteins makes it unlikely it will pass into breast milk. Cholesterol levels in milk are very stable even in hypercholesterolemic women and are not severely affected by diet or nutritional status of the mother, suggesting that 3 is synthesized, at least in part, in the mammary gland (Lawrence 2016, p 289-90).It is not probable therefore, but it is not known if Sch 58235 is able to alter the lipid composition of the milk. Infants need to ingest large amounts of cholesterol, as it is critical to the proper development of the nervous system, cell membranes and is a precursor of several hormones and vitamins. Until there is more data in relation to breastfeeding, it is prudent to avoid using it, at least while breastfeeding exclusively. Suspending the pharmacological treatment of hyperlipidemia during breastfeeding is not likely to alter the long-term outcome of the disease, especially when breastfeeding can be considered therapeutic (Lawrence 2016, p.393). It is advisable to follow a lipid-lowering diet.

No relevant published information exists on the use of Sch 58235 during breastfeeding. Because of a concern with disruption of infant lipid metabolism, Sch 58235 is best avoided during breastfeeding. An alternate drug is preferred, especially while nursing a newborn or preterm infant. Sch 58235 treatment in combination with a statin (e.g., atorvastatin, simvastatin) should be avoided in nursing mothers.