Is 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one? Is 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one safe for nursing mother and child? Does 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one extracts into breast milk? Does 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one has any long term or short term side effects on infants? Can 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one influence milk supply or can 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one decrease milk supply in lactating mothers?
17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one lactation summary
- DrLact safety Score for 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one usage in lactation
Antagonist of opium derivative drugs.
Answer by DrLact: About 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one usage in lactation
No information is available on the excretion of 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one into breastmilk. Because it is not orally bioavailable, it is unlikely to affect the breastfed infant. However, if 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one is required by the mother for an opiate overdose, she should withhold nursing until the opiate is out of her system.
17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one Possible Effects in Breastfeeding
In contrast to its effect in some animal species, 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one does not affect suckling-induced secretion of oxytocin or prolactin in postpartum women.[1][2]