Is D-(-)-Noradrenaline Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use D-(-)-Noradrenaline? Is D-(-)-Noradrenaline safe for nursing mother and child? Does D-(-)-Noradrenaline extracts into breast milk? Does D-(-)-Noradrenaline has any long term or short term side effects on infants? Can D-(-)-Noradrenaline influence milk supply or can D-(-)-Noradrenaline decrease milk supply in lactating mothers?
D-(-)-Noradrenaline lactation summary
- DrLact safety Score for D-(-)-Noradrenaline is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of D-(-)-Noradrenaline is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that D-(-)-Noradrenaline does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of D-(-)-Noradrenaline safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About D-(-)-Noradrenaline usage in lactation
It is destroyed within the gastrointestinal tract. Systemically used on CPR, and locally for topical anesthesia, ophtalmic drops (mydriatic) and nasal drops (vasoconstriction).
Answer by DrLact: About D-(-)-Noradrenaline usage in lactation
No information is available on the use of D-(-)-Noradrenaline during breastfeeding. Because of its poor oral bioavailability and short half-life, any D-(-)-Noradrenaline in milk is unlikely to affect the infant. High intravenous doses of D-(-)-Noradrenaline might reduce milk production or milk letdown.
D-(-)-Noradrenaline Possible Effects in Breastfeeding
Relevant published information in nursing mothers was not found as of the revision date. Animal data indicate that D-(-)-Noradrenaline can decrease serum prolactin and reduce milk production,[1] as well as inhibit the release of oxytocin, which inhibits milk ejection.[2]
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