Question

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 1923? Is CCRIS 1923 safe for nursing mother and child? Does CCRIS 1923 extracts into breast milk? Does CCRIS 1923 has any long term or short term side effects on infants? Can CCRIS 1923 influence milk supply or can CCRIS 1923 decrease milk supply in lactating mothers?

CCRIS 1923 lactation summary

CCRIS 1923 usage has low risk in breastfeeding
  • DrLact safety Score for CCRIS 1923 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of CCRIS 1923 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that CCRIS 1923 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of CCRIS 1923 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using CCRIS 1923 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About CCRIS 1923 usage in lactation

Advice to take a minimal dose for a short time since anti-cholinergic drugs may decrease breast milk production. Check-up for anti-cholinergic symptoms (mouth dryness, constipation...)

Answer by DrLact: About CCRIS 1923 usage in lactation

No information is available on the use of oxybutynin during breastfeeding. Long-term use of oxybutynin might reduce milk production or milk letdown, but a single dose is not likely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

CCRIS 1923 Possible Effects in Breastfeeding

Anticholinergics can inhibit lactation in animals apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed. The manufacturer reports that cases of lactation suppression have been reported with some oxybutynin (immediate-release) formulations in postmarketing surveillance.[7]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.